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769 days ago

Postdoctoral

University of Calgary -

Successful candidates will be recent PhD graduates who are interested in making fundamental discoveries in tumor evolution and immune response that can lead to translational impact in aggressive and largely incurable cancers.

Research approaches in our team include computational analyses of tumor multi-omic profiles at bulk and single cell level, with spatial and temporal resolution within patient samples. We are interested in how tumor cells cooperate with non-neoplastic cells of the microenvironment to respond to selective pressures in general, and in particular to standard therapy regimes. The focus of the candidate will be on establishing methods to integrate long-read sequencing data into our current workflows for genome and transcriptome analyses. Key goals include identification of novel biomarkers and targets for therapy that can be further pursued within a fully operational preclinical pipeline toward clinical translation.

The lab is part of a multi-disciplinary team of cancer researchers filled with passionate and determined individuals who will provide the successful candidate with a stimulating and conducive environment to participate and grow as a scientist. The research is conducted at the University of Calgary, in close collaboration with local and international scientists and clinicians, and thus will also provide the successful candidate with opportunities to learn from a large network of talented professionals.

769 days ago

Postdoctoral

Northwestern University -

We are looking for a highly motivated candidate specializing in Bioinformatics to join Dr. Rendong Yang’s laboratory at the Northwestern University Feinberg School of Medicine located in Chicago, IL. The Yang laboratory is interested in the integrative analysis of large-scale, multi-dimensional genomic data to understand the initiation and progression of diseases. The research projects involve in the development of highly accurate and sensitive computational methods for analyzing large-scale genomic data, especially in the area of detecting and analyzing genetic variations and somatic mutations. Example projects span from technique-driven research that aims developing algorithms for a wide range of applications (e.g. Yang et al., Bioinformatics 2010; Yang et al., BMC Genomics 2014; Yang et al., Genome Medicine 2015), to hypothesis-driven investigation of specific biological problems where the main goal is the discovery and advancement of biological knowledge (e.g. Asangani et al., Nature 2014; Henzler et al., Nature Communications 2016; Katerndahl et al., Nature Immunology 2017, Wang et al. Molecular Cell 2021). More information can be found by visiting the lab website: https://ylab-hi.github.io/

769 days ago

Postdoctoral

Princess Margaret Cancer Centre - UHN -

The Kridel lab is seeking a talented postdoctoral fellow to lead ongoing efforts to enhance our understanding of lymphoma pathogenesis by leveraging large datasets. The research will focus on either of the following topics: (i) dissection of immune correlates underlying both common and rare lymphoma types using single cell sequencing; (ii) development of liquid biopsy-based biomarkers for the accurate classification and monitoring of lymphoma. The post-doctoral fellow will design and carry out experiments to address key questions in the above topics and lead the writing of scientific manuscripts. The successful candidate will be embedded in a rich scientific environment that provides ample opportunities for development of technical, as well as leadership skills. Highly motivated individuals with a desire to make an impact in the field of cancer genomics are encouraged to apply.

769 days ago

Postdoctoral

University of Toronto -

The Yuzwa lab in the Department of Laboratory Medicine and Pathobiology (LMP) at the University of Toronto is seeking to hire a Post-doctoral Fellow to work on an exciting project that will unravel lineage and spatial relationships between cells of the mammalian brain and the impacts of disease on these relationships. The primary approaches that will be applied in these studies are single-cell (scRNA-seq) and spatially-resolved transcriptomics (available in-house), the generation of novel DNA constructs (using molecular cloning), primary neural culture and in vivo studies, along with computational biology/bioinformatics to develop and apply tools to analyze the data.

769 days ago

Postdoctoral

German Research Centre for Geosciences (GFZ) -

The prime goal of the work will be to elucidate microbial processes on the Greenland Ice Sheet in the framework of the European Research Council (ERC) Synergy grant “Deep Purple”. The post holder will become part of a multidisciplinary team in the Interface Geochemistry section at the German Research Centre for Geosciences (GFZ) in Potsdam , Germany and closely interface with members of the Cryo-Microbiology group at Aarhus University in Denmark.

She/he/they will join the international and diverse team of researchers led by Liane G. Benning, who is very committed to fostering a fully inclusive research environment. Non-discrimination and equal treatment are integral parts of our group policy.

We are seeking a highly motivated and enthusiastic bioinformatic focussed scientist who wants to develop her/his/their skills in a complementary research environment, where different disciplines work closely together to obtain a holistic understanding of cryogenic microbial processes and interactions in snow and ice environments.

The focus will be on eukaryotes and bioinformatic analyses of sequencing data from various ‘omic’ approaches that target the interactions between algae and other cryophillic microbes.