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Institution/Company:

The University of British Columbia

Location:

Vancouver

, British Columbia

 Canada

Job Type:

Postdoctoral

Degree Level Required:

PhD

72 days ago Apply now

Description:

Postdoctoral Fellow/Computational Biology

The Department of Microbiology & Immunology is seeking a highly qualified and motivated full-time Bioinformaticist to start as soon as possible. The successful candidate will join the Hancock research group and will perform algorithmic and statistical analyses on genomic and transcriptome sequencing data sets.  The primary project for this position will be identifying endotype specific drug targets in sepsis and other side projects may involve other sepsis projects, human vaccine responses, bacterial studies and novel peptide therapeutics that target inflammation.  This position involves running genome sequencing data analysis pipelines, testing and maintenance of existing sequence-analysis pipelines, automation of routine programming and data-analysis tasks and workflows, managing and processing genomic data, interpretation of results and, where necessary, contributing to the development of software implementing novel algorithms and statistical models. The successful candidate will provide consultation to researchers on study design, analysis and statistical methods.

All qualified candidates are encouraged to apply; however Canadians and permanent residents will be given priority. Please include citizenship/PR status information in your application.

To Apply:  Submit a CV, a short (one-two-page) description of research interests and experience, and contact information for at least two references by e-mail to: careers@hancocklab.com

Please use the words: PDF sepsis endotypes in the subject header

 

Responsibilities:

  • perform algorithmic and statistical analyses on genomic and transcriptome sequencing data sets
  • running genome sequencing data analysis pipelines
  • testing and maintenance of existing sequence-analysis pipelines
  • oversee updating/development of software requiring R or python programming
  • provide consultation to researchers on study design, analysis and statistical methods to other lab members and collaborators
  • attend two weekly lab meetings (In person or and/or Zoom)
  • prepare figures and write up data  as manuscripts for publication in peer reviewed journals
  • work with principal investigator to ensure that all scientific milestones are achieved
  • present findings at local, national and international scientific meetings
  • perform other related duties.

Qualifications:

Recent completion (< 3 years) of a PhD in a biological science discipline (Biology/Immunology/Biochemistry/Cell Biology)

Track record of publishing in top-level, peer-reviewed journals. Demonstrated expertise in bacterial genetics, immunology and cell biology. Demonstrated experience in analyzing transcriptomic data sets. Demonstrated ability to work productively in a collaborative research team.  Additional experience required:

  • Experience in working with next generation sequencing data and related analysis tools and workflows
  • 2+yrs experience working in a research or corporate environment
  • Strong knowledge of Unix/Linux operating system
  • Considerable programming/scripting skills in R and Python
  • Familiarity with human genome databases (Ensembl, UCSC genome browser, NCBI)
  • Familiarity with parallel computing environments (Linux clusters, SunGridEngine, etc
  • Experience with bioinformatics tools such as Bioconductor considered an asset
  • Experience in development of algorithms/machine learning/statistical models for bioinformatics considered an asset
  • Experience with RNA-Seq data analysis an asset
  • Experience with data sets from human biological samples an asset

 

Additional Information:

UBC (www.ubc.ca) hires on the basis of merit and is strongly committed to equity and diversity within its community. We especially welcome applications from visible minority group members, women, aboriginal persons, persons with disabilities, persons of minority sexual orientations and gender identities, and others with the skills and knowledge to productively engage with diverse communities.

The Department of Microbiology and Immunology (https://www.microbiology.ubc.ca/) at the University of British Columbia provides a stimulating environment in which to pursue a graduate or undergraduate research program. Our faculty is internationally recognized for contributions in microbiology, molecular biology and immunology.

The Hancock lab (http://cmdr.ubc.ca/bobh/) is located on the Vancouver Point Grey campus.  It is part of the Department of Microbiology and Immunology and the faculty is internationally recognized for contributions in microbiology, molecular biology and immunology. The fundamental interest of the Hancock laboratory is in designing new therapeutic strategies to treat infections in the light of increasing antibiotic resistance coupled with a dearth of new antibiotic discovery. One of the research themes includes utilizing functional genomic and bioinformatics studies to define the innate immunity/inflammatory network.

Keywords:

Bioinformatics

sepsis

endotypes

drug targets

RNA-Seq

transcriptomics

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