104 days ago
Institution/Company:

Yale University

Location:

New Haven

, CT

 United States

Job Type:

Postdoctoral

Degree Level Required:

PhD

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Description:

Postdoctoral Positions in Etienne Caron Lab at Department of Immunobiology, Yale School of Medicine. The Caron Lab seeks postdoctoral applicants with a passion for innovation in mass spectrometry-based immunopeptidomics research. The overarching goal of the Caron Lab is to develop and apply mass spectrometry-based methods and systems immunology approaches to understand the generation, composition and dynamics of both the self and nonself immunopeptidome, as well as its interaction with T cells, with the ultimate goal of innovating treatments and preventive strategies for a broad range of immune-related diseases.

Opportunities and Benefits. Postdocs will have the opportunity to gain expertise in mass spectrometry, systems immunology, spatial immunopeptidomics, T-cell epitope discovery, immunology, and vaccine design. The selected candidates will also have the opportunity to become active players within several Yale Centers, including the Yale Center for Immuno-Oncology (YCIO), Center for Infection and Immunity (CII), and Center for Systems and Engineering and Immunology (CSEI). Strong support will be given to purse independent directions. Postdoc compensation and benefits will be according to Yale policies. More information about salaries and other resources can be found at https://postdocs.yale.edu/.

 

 

Responsibilities:

Expectations. The successful candidates are expected to work on the development and application of bioinformatic (integrative multi-omic methods) and/or computational mass spectrometry workflows (machine- and deep-learning methods) for the analysis of immunopeptidomic data generated by a timsTOF Ultra mass spectrometer (Bruker).

Qualifications:

We are seeking passionate individuals with a solid background in computational sciences who are already familiar with state-of-the-art packages and analysis pipelines in mass spectrometry-based proteomics and/or immunopeptidomics. Among the required qualifications are the following:

  • PhD in computer science, bioinformatics or a related field.
  • Work experience in proteomics and/or immunopeptidomics
  • Programming skills (Python, R, Java, C, C++).
  • Expert GitHub user.
  • Strong communication skills in English (spoken and written).
  • Ability to work independently and collaboratively.
Additional Information:

About the Caron Lab:

Dr. Caron is an Assistant Professor at Yale who has recently moved from University of Montreal, Canada. Over the last five years, the Caron Lab has published 14 immunopeptidomics manuscripts including 10 as corresponding papers in Journal of Experimental Medicine, Cell Systems, Cancer Discovery, and other high-profile journals. Dr. Caron is co-founder and former chair (2015-2020) of the Human Immunopeptidome Project. He has a total citation of >4400 times to date and is the recipient of multiple Awards and Recognitions. Please see https://medicine.yale.edu/profile/etienne-caron/ for more information.

If interested, please send your CV and a motivation letter to etienne.caron@yale.edu.

Yale University is an affirmative action/equal opportunity employer and welcomes applications from women, persons with disabilities, protected veterans and members of minority groups.

Keywords:

mass spectrometry

vaccine

peptide

immunopeptidomics

multi-omics

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