618 days ago

The Hospital for Sick Children



, Ontario


Job Type:


Degree Level Required:

Masters, PhD

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Position Description

The Research Associate (Genomicist, Genome analyst, Research Genetic counsellor) will play a key role in the design, planning, and implementation of the Ted Rogers Cardiac Genome Research Clinic (a unique collaboration with SickKids, University Health Network, and the University of Toronto). The Research Associate will liaise with The Centre for Applied Genomics (TCAG) and internal and external project stakeholders to ensure the project aligns to achieve the targeted outcomes.

The primary responsibility for this role will be to support the development, implementation and maintenance of the analysis pipeline of the cardiac genomic sequencing data. This involves working closely with a team of research genome scientists from TCAG, the Labatt Family Heart Centre, the Centre for Genetic Medicine, bioinformaticians and clinicians to analyze and interpret genetic and phenotype data from a diverse population with cardiac disease.

As this area of cardiac genetic analysis is rapidly developing, the Research Associate will be responsible for keeping abreast of new developments in genomic analysis as it applies to cardiology and incorporating advances in the field into clinical service.

Reports to: Ted Rogers Centre for Heart Research Cardiac Genome Clinic Clinical Investigator(s)


Responsibilities of the Cardiac Research Associate:

  • To work with ongoing collaborations with clinicians, research scientists and bioinformaticians to identify new genomic analytic methodology.
  • To coordinate the in-depth analysis of samples with team members conducting and interpreting genomic analysis and variant interpretation.
  • To conduct the development, validation and implementation of new genomic analytic tools and technologies for use in the laboratory and ensure that they meet the needs of the clinical programs of the Hospital.
  • To participate in strategic planning, implementation and ongoing development of the Cardiac Genome Clinic, particularly as it relates to implementation of latest sequencing technologies into clinical diagnostics to directly benefit Canadian and international health care.
  • To work within the framework of the Ted Rogers Centre for Heart Research and TCAG, and with stakeholders from the Division of Clinical and Metabolic Genetics, the Centre for Computational Medicine (CCM), and the Labatt Family Heart Centre to introduce and support clinical whole genome sequencing into its molecular diagnostics laboratory to serve the Cardiac Genome Clinic and SickKids/UHN in general.
  • To ensure that written procedures/protocols are developed and approved for each methodology implemented and the ongoing review and approval of all changes at an established frequency to ensure protocols remain current with advances in technology and laboratory practice.
  • To liaise with the Genome Diagnostics/TCAG to establish appropriate procedures for recording and reporting of genomic test results within defined time expectations (TATs).
  • To work with the clinical investigators/collaborators on translational research initiatives, including the follow-up of new genomic testing and reporting and in the development of new knowledge to extend the utility of cardiac genomic testing.
  • To establish resources (patient and control cohort collections, data sets, and infrastructure) available for broad use in the long term by the Canadian and international scientific and clinical communities
  • To continually update professional knowledge and skills through reading scientific literature and attending national and international conferences.
  • To augment the stature of the hospital through excellence in genomic research, teaching and/or participation in national and international genetic organizations.

Here’s What You’ll Need

  • PhD and post-doctoral training in human molecular genetics, population genetics, cardiac genomics, or related field (preferred),
  • Or Master’s in Genetic Counselling (ABGC, CAGC) with experience in variant interpretation,
  • Or Master’s in Medical Genomics with experience in variant interpretation


  • Previous training or experience in human genomic analysis (experience with cardiac disease an asset).
  • Demonstrated ability to conduct independent research and experience in the development of research manuscripts.
  • Broad understanding of the latest research tools and techniques and developments in genomic technology bioinformatics and variant interpretation as it pertains to genetic cardiac diagnostics.
  • Strong problem-solving skills and the ability to analyze complex problems.
  • Excellent communication skills and the ability to work in a team environment.

Employment Type: 1-year contract with modified benefits

Additional Information:

About SickKids

Dedicated exclusively to children and their families, The Hospital for Sick Children (SickKids) is one of the largest and most respected paediatric healthcare centres in the world.  As innovators in child health, we lead and partner to improve the health of children through the integration of healthcare, leading-edge research and education.  Our reputation would not have been built – nor could it be maintained – without the skills, knowledge and experience of the extraordinary people who come to work here every day.  SickKids is committed to ongoing learning and development, and features a caring and supportive work environment that combines exceptionally high standards of practice.

When you join SickKids, you become part of our community. We share a commitment and determination to fulfill our vision of Healthier Children. A Better World.

Don’t miss out on the opportunity to work alongside the world’s best in paediatric healthcare.

Our Commitment to Diversity

The children and families we care for are from a variety of communities, and so are our employees. We welcome and encourage everyone to join our organization and be part of our team.

When requested, SickKids will provide access and inclusion supports to eligible candidates to support their full engagement during the interview and assessment process.  Information received related to access or inclusion will be addressed confidentially.

Thank you for your interest in joining SickKids. Only those applicants selected for an interview will be contacted. In accordance with our Hospital policy, employment at SickKids is conditional upon the Hospital’s receipt of all necessary documentation.

FOR EXTERNAL APPLICANTS ONLYAs a health care institution, our highest priority is the safety of patients, families and staff.  As a result, we are adopting all prevention measures to ensure the safety of our patients, families and our staff.  Therefore, any offer of employment is conditional upon you submitting proof that you have been fully vaccinated with a Health Canada or World Health Organization (WHO) approved COVID-19 vaccination as soon as possible and no later than fourteen (14) calendar days prior to the effective start date, in addition to satisfying any other condition(s) that may be set out in an offer.  If a candidate fails to satisfy this condition (or any other condition(s) set out in an offer), any offer of employment shall be immediately rescinded.

How to Apply

Tip: Combine your cover letter and resume into ONE document of 20 pages or less as you cannot upload multiple documents as part of your application.

If you are still experiencing technical difficulties please email ask.hr@sickkids.ca to send us a short description of the issues you are experiencing. Please note that we will not accept resumes sent to this inbox but we are happy to respond to requests for technical assistance.


genome analysis


cardiac genetics

genomic research

congenital heart disease

heart disease

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