Jobs

Under the direction of the Bioinformatics Manager, the Bioinformatics Specialist will be a senior member of the technical development group at Canadian Centre for Computational Genomics (C3G), a bioinformatics platform hosted at the McGill Genome Centre (MGC). The chosen candidate will lead development for large scale projects, as well as design, test, and perform advanced bioinformatics analyses that enable the interpretation of data generated by various biological assays. Working closely with other members of the McGill Genome Centre, the chosen candidate will be exposed to a wide variety of novel sequencing technologies, bioinformatics approaches, and state of the art computing resources in a facility dedicated to high-throughput sequencing and large-scale genomic studies.

Position:              Software Architect II
Site:                      MaRS Centre, Toronto
Department:         Genome Informatics
Reports To:          Director, Genome Informatics and Principal Investigator Level I
Salary:                  Commensurate with level of experience
Hours:                   35 hours/week
Status:                  Full-time, Permanent

We are growing! With new projects and lots of exciting technologies, the Ontario Institute for Cancer Research (OICR) is looking for a passionate and talented Software Architect to join the Genome Informatics team to continue building cutting edge tools and infrastructures used by researchers around the globe to fight cancer.

Our open source applications handle vast amounts of data (2+ PB) and run on large compute environments. Designed and implemented by our in-house developers, we maintain a diverse set of tools and projects, from complex ETL systems to modern user interfaces. The Genome Informatics team has worked on a variety of projects including:

• ICGC-DCC (github, application) – Our most mature and well known project is a submission system comprised of an ETL pipeline and data portal coordinating cancer research on 86 projects with participants from all over the world. With ICGC-ARGO ICGC is entering a new phase with an engaging and complex set of software engineering challenges ahead of us, such as providing researchers with access to 100’s of billions of genetic variants.
• ICGC-ARGO (github, application) – The next generation and evolution of the original ICGC-DCC, this platform aims to uniformly analyze specimens from 100,000 donors with high quality clinical data in order to address outstanding questions that are vital to the quest to defeat cancer.
• Cancer Genome Collaboratory (github, website) – A compute and storage cloud operated by the team which is progressively enhanced with more tools to assist researchers running analysis pipelines.

• VirusSeq Data Portal for COVID-19 (github, application) – The goal of the CanCOGeN VirusSeq project is to sequence up to 150,000 viral samples from Canadians testing positive for COVID-19 and make the sequences and associated non-personal contextual data available for research and exploration in an open-source and open-access data portal.
• Human Cancer Models Initiative (HCMI) Catalog (github,application) – A searchable catalog of cancer models.

As part of the Genome Informatics team, the successful candidate will be joining some of the above-mentioned projects, but also be contributing to Overture.bio (github, website), our suite of open-source components for big data genomic science in the cloud.

We are looking for a passionate Software Architect to join our agile development team. In this role, you will serve as a technical guiding force for multiple ongoing projects as well as be responsible for spearheading and championing technical innovation.

OICR has a mandatory COVID-19 vaccination policy in place that requires proof of full COVID-19 vaccination or proof of a medical exemption issued pursuant to the Government of Ontario guidelines.  Accordingly, as a condition of employment, new employees who may be required to work on-site are required to be fully vaccinated for COVID-19 subject to the duty to accommodate on the basis of protected grounds pursuant to the Ontario Human Rights Code.

Fully vaccinated is defined as having received all of the required doses of a Health Canada approved vaccine and having received the final dose at least 14 days before your employment start date.

As described above, the requirement to be fully vaccinated is subject to the Ontario Human Rights Code. If the candidate is unable to receive the COVID-19 vaccine for a reason protected by the Code, requests for accommodation from the vaccine policy will be assessed on a case-by-case basis.

To learn more about working at OICR, visit our career page.

Position:        Outreach Lead
Site:               MaRS Centre, Toronto
Department:  Genome Informatics
Reports To:    Director, Genome Informatics
Salary:           Commensurate with level of experience
Hours:           35 hours/week
Status:           Full-time, Permanent

We are growing! With new projects and lots of exciting technologies, the Ontario Institute for Cancer Research (OICR) is looking for passionate and talented software developers across the entire software stack to join the Genome Informatics Software Engineering team to continue building cutting edge tools and infrastructures used by researchers around the globe to fight cancer. Our open source applications handle vast amounts of data (2+ PB) and run on large compute environments. Designed and implemented by our in-house developers, we maintain a diverse set of tools and projects, from complex ETL systems to modern user interfaces. The Genome Informatics team work on a variety of projects including:

• ICGC-DCC (github, application) – Our most mature and well known project is a submission system comprised of an ETL pipeline and data portal coordinating cancer research on 86 projects with participants from all over the world. With ICGC-ARGO (github,application), ICGC is entering a new phase with an engaging and complex set of software engineering challenges ahead of us, such as providing researchers with access to 100’s of billions of genetic variants.
• ICGC-ARGO (github, application) – The next generation and evolution of the original ICGC-DCC, this platform aims to uniformly analyze specimens from 100,000 donors with high quality clinical data in order to address outstanding questions that are vital to the quest to defeat cancer.
• Cancer Genome Collaboratory (github, website) – A compute and storage cloud operated by the team which is progressively enhanced with more tools to assist researchers running analysis pipelines.

• VirusSeq Data Portal for COVID-19 (github, application) – The goal of the CanCOGeN VirusSeq project is to sequence up to 150,000 viral samples from Canadians testing positive for COVID-19 and make the sequences and associated non-personal contextual data available for research and exploration in an open-source and open-access data portal.
• Human Cancer Models Initiative (HCMI) Catalog (github,application) – A searchable catalog of cancer models.

All those projects are underpinned by our flagship product, the Overture software suite (https://www.overture.bio/). Overture is a collection of open-source, extendable solutions for big-data genomic science that can easily be reused to support research. As the Overture suite and usage grows, we are looking for an enthusiastic outreach officer to lead our outreach and user-facing efforts.

The Overture Outreach Coordinator will be involved in teaching, training, and helping bioinformatic users. They will contribute to the presentation of the Overture product, both written and orally, to international collaborators and interested parties. They will support writing of documentation and scientific publication about Overture and projects using it.

New employees who may be required to work on-site are required to be fully vaccinated for COVID-19 subject to the duty to accommodate on the basis of protected grounds pursuant to the Ontario Human Rights Code.

Fully vaccinated is defined as having received all of the required doses of a Health Canada approved vaccine and having received the final dose at least 14 days before your employment start date.

As described above, the requirement to be fully vaccinated is subject to the Ontario Human Rights Code. If the candidate is unable to receive the COVID-19 vaccine for a reason protected by the Code, requests for accommodation from the vaccine policy will be assessed on a case-by-case basis.

To learn more about working at OICR, visit our career page.

Under the direction of the Bioinformatics Manager, the Bioinformatics Analyst will be a member of the services team at Canadian Centre for Computational Genomics (C3G), a bioinformatics platform hosted at the McGill Genome Centre (MGC). The chosen candidate will perform advanced bioinformatics analyses that enable the interpretation of data generated by various biological assays, in addition to supporting the development of analysis pipelines at the platform. Working closely with other members of the McGill Genome Centre, the chosen candidate will be exposed to a wide variety of novel sequencing technologies, bioinformatics approaches and state-of-the-art computing resources in a facility dedicated to high-throughput sequencing and large-scale genomic studies.

The Caron Lab (www.caronlab.org) is seeking a senior bioinformatician who will be in charge of all bioinformatics aspects in the laboratory of Dr Etienne Caron.

Etienne Caron is Principal Investigator at the CHU Sainte-Justine Research Center and Associate Investigator at the Institute for Research in Immunology and Cancer (IRIC). Dr. Caron’s laboratory has an internationally recognized expertise in systems biology and immunopeptidomics. His team is interested in the development and application of next generation mass spectrometry technologies for the discovery of novel immunotherapeutic targets in cancers and infectious diseases, pediatric leukemias and COVID-19 in particular. More recently, Dr. Caron joined the CoVaRR-Net canadian network to investigate the impact of SARS-CoV-2 mutations on T cell immunity.