Jobs

Company Biography: Shared Hospital Laboratory Inc. (SHL) is an independent corporation owned and operated by Scarborough Health Network, North York General Hospital, Michael Garron Hospital and Sunnybrook Health Sciences Centre. SHL provides high quality, efficient, advanced microbiology services. SHL has proven to be one of the most successful and sustainable models of laboratory collaboration in Ontario. SHL has a Board approved strategic plan focused on growth through optimizing/expanding clinical scope, fostering new partnerships, and advancing technology/infrastructure to ensure long-term sustainability.

Position Overview: Reporting to the Medical Director at Shared Hospital Laboratory, this person will assist and provide support for the bioinformatics analysis of bacterial and viral pathogens that are of relevance to SHL and develop a research program relevant to the strategic plan of SHL.

Under the supervision of Dr. S. Jacquemont, the Bioinformatician/Data Manager will be responsible for identifying, annotating, and analyzing genetic variants from genotyping and sequencing data (exome and whole genome). The project explores the impact of genetic variants on cognition, behavior, and psychiatric and neurodevelopmental traits.

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Projet
Laboratoire de recherche du Dr Sébastien Jacquemont.
http://minds-genes.org/

Description du poste
Sous la responsabilité du directeur du Dr Jacquemont, le bioinformaticien/data-manager devra identifier, annoter et analyser des variants génétique à partir de données de génotypage et de séquençage (exome et génome complet). Le projet explore l’impact de variants génétiques sur la cognition, le comportement et les traits psychiatriques et neurodéveloppementaux. Le candidat sera responsable de :

The Office of the Associate Dean in the Cumming School of Medicine invites applications for two (2) Intermediate Programmer Analyst(s). This Full-time Fixed Term position is for approximately 12 months (based on length of grant funding), with the possibility of extension.

Reporting to the Manager, Bioinformatics.

The CHGI bioinformatics team provides sequencing project design, quality control, statistical analysis, public repository submission, and biological interpretation services (linking new results to known results in the literature) to users of the Cumming School of Medicine’s core CHGI sequencing facility.

Position:                     Bioinformatician II
Location:                    MaRS Centre, Toronto
Department:               Genome Sequence Informatics
Reports To:                Senior Manager
Salary:                        Commensurate with level of experience
Hours:                        35 hours/week
Job Type:                   Hybrid
Status:                        Full-time, Permanent

OICR is seeking an experienced and passionate Bioinformatician to join the Genome Sequence Informatics (GSI) team at OICR. The Bioinformatician functions in a junior to intermediate technical role that requires an individual with proven skills in both biology and computing, and who is dedicated to supporting a multi-disciplinary team of scientists, laboratory technicians, and informatics professionals.

GSI is part of the Genomics program at OICR (https://genomics.oicr.on.ca/) and supports the sequencing teams that manage both clinical and research projects. GSI designs applications to streamline and automate analysis, control the data lifecycle, and create useful and dynamic reports at scale. We ensure that data flows smoothly, securely and correctly from the lab through to the clinicians and researchers who use it. We use languages and software tools like Java, Python, Perl, Javascript, OpenStack, Open Grid Engine, Univa, MySQL and PostgreSQL.

The main areas covered by GSI are:

• Lab tracking: Develop the open source MISO LIMS (https://miso-lims.github.io) augmented by other applications.
• Pipeline/Data management: Develop and run workflow systems like Vidarr (https://oicr-gsi.github.io/vidarr/) and Cromwell (https://cromwell.readthedocs.io) to automate and streamline data analysis, tracking, and workflow management.
• Data release: Delivery of sequencing and analysis, archiving of data for long term storage and deposition of data to public archives.
• Reporting: Maintain of a suite of specialized reports for quality control, forecasting, and lab operations, and to accompany data delivery.
• Analysis: Development of analysis workflows to run in our pipeline system, and development of tools supporting analysis tracking and data management. Conducting project-specific analysis on sequencing data with an emphasis on cancer genomics, both for internal research projects and for collaborators.
• Cancer Genome Interpretation: Analyze and interpret genomic data using accredited pipelines and processes for clinical purposes.