Jobs

https://www.chumontreal.qc.ca/en/emplois/postdoctoral-fellowresearch-associate-chum-microbiome-centre-dr-bertrand-routy-and-dr

The CHUM Microbiome Centre led by Drs. Bertrand Routy and Dr. Arielle Elkrief are looking for a postdoctoral or associate level research candidate in bioinformatics and computational oncology to analyze microbiome samples sequenced by metagenomics.

The team currently leads several prospective clinical studies (NCT04951583, NCT05303493 and NCT05805319) testing different strategies, including fecal transplantation, prebiotics, probiotics and diet, to improve the composition of the microbiome for patients with lung cancer and melanoma treated with immunotherapy.

The specific role of the candidate will be to perform computational analyses on samples from various pan-Canadian randomized clinical trials evaluating the evolution of the microbiome before and after the different treatments and over time. In addition, she/he will have to supervise students at MSc and PhD levels in bioinformatics.

Our team recently received a large $3,800,000 grant to conduct one of the largest randomized clinical trials in the world to study FMT plus immunotherapy. The candidate will successfully integrate longitudinal multiomics analysis to understand the mechanism of FMT.

Position Overview: We are looking to hire a postdoctoral fellow interested in working on a collaborative project to call RNA modifications from Oxford Nanopore Sequencing data. Interested candidates with a doctoral degree in any areas of biology relating to transcriptomics, bioinformatics, and RNA biology are encouraged to apply. This position offers an exciting opportunity to understand the role of RNA modifications in development, behavior, and/or health and disease. Opportunities for expanding the position into wet lab workflows (ONT sequencing) and wet lab method development and optimization are available.

The bioinformatics postdoc will be part of an interdisciplinary research team that is using wastewater to track the dynamics of infectious agents. We have developed an integrated surveillance network monitoring 43 municipalities, as well as several sentinel surveillance hubs including a large number of tertiary care hospitals and populations of special interest from which we collect samples 1-3x per week. The successful applicant will join a productive transdisciplinary team with supporting research funding from CIHR, Genome Canada, and Alberta Health. The postdoc will work as part of a large team that includes several staff with PhDs, graduate students, and undergraduates. They will report to Michael Parkins (Section Chief of Infectious Diseases, Cumming School of Medicine) and Srijak Bhatnagar, Bioinformatics lead, Faculty of Science and Technology).

The position is based at the University of Calgary.

Job Summary

The laboratory of Dr. Paul Pavlidis, in the Departments of Psychiatry and the Michael Smith Laboratories at the University of British Columbia, is seeking an ambitious and highly motivated Postdoctoral Fellow in computational biology/bioinformatics. The Pavlidis lab works on the development, evaluation, and application of computational methods to understand gene function and regulation, with a biological focus on the nervous system. More information on the lab is available at https://pavlab.msl.ubc.ca.

The Michael Smith Laboratories (MSL; https://www.msl.ubc.ca/) is a dynamic hub for groundbreaking research and education excellence. Our highly interdisciplinary and collaborative research environment supports faculty with focus in genomics, molecular biology, engineering, and biotechnology. More than 350 faculty, postdocs, students, and research personnel make the MSL their home with appointments across the Faculties of Science, Medicine, Applied Science, Forestry, Land and Food Systems, and Pharmaceutical Science. The MSL has a proven record of accomplishment in fundamental and applied research that has led to transformative impacts for Canada and the world.

Position Title: Bioinformatics/Biologist

Department: Pathobiology
Description of the Area/Topic of Research:

The Ricker lab at the University of Guelph is currently recruiting 1 PhD student and 1 post-doctoral fellow or research associate, in collaboration with Dr. Hany Anany (AAFC), for projects recently funded through the Canadian Poultry Research Council (CPRC) and Agriculture-AgriFood Canada (AAFC).

Antimicrobial resistance (AMR) is one of the largest human health concerns of this generation, as the continued emergence of resistance threatens to interfere with our ability to treat and prevent human infectious diseases. Combating AMR requires a One Health approach, combining efforts at limiting resistance emergence and spread within human, animal and environmental reservoirs.

We are currently seeking two candidates (a PhD student and a postdoctoral fellow) for a 4-year project investigating the use of phage to control Salmonella within the poultry industry. The successful candidates will meet or exceed the minimum academic requirements for entry to a PhD program, have a relevant publication record appropriate to their current career stage, and have previous experience working with phage. An interest in the combination of microbiology techniques and bioinformatic approaches is essential. Experience in metagenomics, phage biology, phage-host interactions, designing and performing bacterial challenge studies and/or viromics are all considered strong assets. Work will be performed at both the University of Guelph and AAFC in Guelph under joint supervision of Drs. Ricker and Anany.

Funding for this project is pending final confirmation and a start date of May 1, 2024 is preferred but is negotiable.

Description of Lab/Group/Area: Dr Ricker is an early career researcher recruited to the University of Guelph through the Food from Thought program for her expertise in microbial community analysis and antimicrobial resistance (AMR) in agriculture.  Her developing research program focuses on AMR prevalence in bacterial communities, horizontal gene transfer mechanisms, promotion of healthy gut microbial communities, and the impact of mitigation strategies on the emergence, persistence, and dissemination of AMR and pathogens in a One Health framework.

Dr. Anany is a Bacteriophage Research Scientist at the Guelph Research and Development Center (GRDC), Agriculture and Agri-Food Canada. In addition, he serves as an Adjunct Professor at the Food Science Department, University of Guelph. His research program focuses on understanding phage biology and its interaction with bacterial hosts for taxonomical and application purposes throughout the food supply chain. Dr. Anany’s research program also extends to exploring the composition and dynamics of the phageome /virome throughout the food supply chain, aiming to deepen our understanding of these complex viral communities and their role in food safety.