Jobs

Postdoctoral position available

The Baloni lab  at the School of Health Sciences and the Purdue Institute for Integrative Neuroscience, Purdue University, is seeking a Postdoctoral Fellow to conduct research on in silico human brain model using multiomics data, ranging from transcriptome to phenome, with a focus on neurodegenerative diseases. The applicant will also be involved in an interdisciplinary project involving human gut microbiome research. The projects are federally funded, and the lab environment is highly supportive.

To apply, please email your CV, cover letter, two representative publications, contact information for three references to the PI Priyanka Baloni (pbaloni@purdue.edu)

Antimicrobial resistance (AMR) is one of the largest human health concerns of this generation, as the continued emergence of resistance threatens to interfere with our ability to treat and prevent human infectious diseases.

Combating AMR requires a One Health approach, combining efforts at limiting resistance emergence and spread within human, animal and environmental reservoirs. As all use (including responsible use) contributes to potential resistance, and transfer can occur between sectors, developing a standardized surveillance platform is imperative. We are currently seeking two computational hires to work collaboratively on two separate, yet integrated, research programs. The first project builds on the recently developed amplicon-based platform termed Diversity of Antibiotic Resistance genes and Transfer Elements – Quantitative Monitoring, abbreviated as DARTE-QM (Smith et al. 2022 Communications Biology, 5 (1): 1-9). This initial version of the platform targeted 662 antibiotic resistance genes and was employed across a diversity of complex environmental samples including manure, soil and livestock feces and illustrated the potential of this platform to both distinguish the resistomes of each source and to allow for comparisons of resistance diversity and abundance across sectors. We are now initiating the second phase of development, aimed at prioritizing our primer targets based on risk characterization and prevalence, and further optimization of the platform. This work will be performed in collaboration with the Canadian Integrated Program for Antimicrobial Resistance (CIPARS) and the Comprehensive Antimicrobial Resistance Database (CARD) and a diversity of researchers from Iowa State University, University of Guelph, and McMaster University. The second project will develop schema and computational pipelines for the incorporation of antimicrobial resistance data into the AgriFood Canada Database for use across a diverse collection of collaborators, including the National Microbiology Laboratory, Public Health Agency of Canada and Animal Health Laboratories.

Funding for these projects, including competitive post-doctoral salaries, has already been secured and a start date of January 1, 2023 is preferred but is negotiable.

Postdoctoral Fellow/Computational Biology

The Department of Microbiology & Immunology is seeking a highly qualified and motivated full-time Bioinformaticist to start as soon as possible. The successful candidate will join the Hancock research group and will perform algorithmic and statistical analyses on genomic and transcriptome sequencing data sets.  The primary project for this position will be identifying endotype specific drug targets in sepsis and other side projects may involve other sepsis projects, human vaccine responses, bacterial studies and novel peptide therapeutics that target inflammation.  This position involves running genome sequencing data analysis pipelines, testing and maintenance of existing sequence-analysis pipelines, automation of routine programming and data-analysis tasks and workflows, managing and processing genomic data, interpretation of results and, where necessary, contributing to the development of software implementing novel algorithms and statistical models. The successful candidate will provide consultation to researchers on study design, analysis and statistical methods.

All qualified candidates are encouraged to apply; however Canadians and permanent residents will be given priority. Please include citizenship/PR status information in your application.

To Apply:  Submit a CV, a short (one-two-page) description of research interests and experience, and contact information for at least two references by e-mail to: careers@hancocklab.com

Please use the words: PDF sepsis endotypes in the subject header

The Genetics and Genome Biology Program at the Hospital for Sick Children (SickKids) Research Institute is seeking an enthusiastic postdoctoral researcher to work in close collaboration with research and clinician scientists in analyzing next generation sequencing data of individuals with genetic disorders.

With the direction of principal supervisor Dr. Ryan Yuen, you will work closely with affiliated staff, as well as bioinformaticians at SickKids, to study the genetics of neurodevelopmental and neurological disorders.

Dedicated exclusively to children and their families, The Hospital for Sick Children (SickKids) is one of the largest and most respected paediatric healthcare centres in the world. As innovators in child health, we lead and partner to improve the health of children through the integration of healthcare, leading-edge research and education. Our reputation would not have been built – nor could it be maintained – without the skills, knowledge and experience of the extraordinary people who come to work here every day. SickKids is committed to ongoing learning and development, and features a caring and supportive work environment that combines exceptionally high standards of practice.
When you join SickKids, you become part of our community. We share a commitment and determination to fulfill our vision of Healthier Children. A Better World.
Don’t miss out on the opportunity to work alongside the world’s best in paediatric healthcare.
SickKids is strongly committed to diversity within its community and welcomes applications from visible minority group members, women, Aboriginal persons, persons with disabilities, members of sexual minority groups and others who may contribute to diversity within our organization.
SickKids is also committed to providing services in both official languages and our preference is to hire employees who are fluent in both English and French whenever possible.

The Bioinformatics Lab of McDermott Center for Human Growth and Development at University of Texas Southwestern Medical Center at Dallas solicits applications for postdoctoral fellowship in statistical genomics, genetics, and computational biology.

We seek highly motivated individuals with strong problem-solving skills to develop, implement and apply innovative approaches for analyzing high throughput genetic and genomic data. Multiple project directions are available in statistical genetics (such as genetic epidemiology study in diverse, multi-ancestry datasets using genome-wide sequencing data, gene-environment interaction, meta-analysis) and genomics (such as single-cell omics analysis, multi-omics data integration, network analysis).

The training activities of this position will include data management, analysis, development and/or implementation of novel analytical approaches and bioinformatics tools for data analysis, implementation of pipelines, interpretation and presentation of analysis results, and writing manuscripts.