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860 days ago

Postdoctoral

The Hospital for Sick Children -

The Genetics and Genome Biology Program at the Hospital for Sick Children (SickKids) Research Institute is seeking an enthusiastic postdoctoral researcher to work in close collaboration with research and clinician scientists in analyzing next generation sequencing data of individuals with genetic disorders.

With the direction of principal supervisor Dr. Ryan Yuen, you will work closely with affiliated staff, as well as bioinformaticians at SickKids, to study the genetics of neurodevelopmental and neurological disorders.

Dedicated exclusively to children and their families, The Hospital for Sick Children (SickKids) is one of the largest and most respected paediatric healthcare centres in the world. As innovators in child health, we lead and partner to improve the health of children through the integration of healthcare, leading-edge research and education. Our reputation would not have been built – nor could it be maintained – without the skills, knowledge and experience of the extraordinary people who come to work here every day. SickKids is committed to ongoing learning and development, and features a caring and supportive work environment that combines exceptionally high standards of practice.
When you join SickKids, you become part of our community. We share a commitment and determination to fulfill our vision of Healthier Children. A Better World.
Don’t miss out on the opportunity to work alongside the world’s best in paediatric healthcare.
SickKids is strongly committed to diversity within its community and welcomes applications from visible minority group members, women, Aboriginal persons, persons with disabilities, members of sexual minority groups and others who may contribute to diversity within our organization.
SickKids is also committed to providing services in both official languages and our preference is to hire employees who are fluent in both English and French whenever possible.

866 days ago

Postdoctoral

University of Texas Southwestern Medical Center -

The Bioinformatics Lab of McDermott Center for Human Growth and Development at University of Texas Southwestern Medical Center at Dallas solicits applications for postdoctoral fellowship in statistical genomics, genetics, and computational biology.

We seek highly motivated individuals with strong problem-solving skills to develop, implement and apply innovative approaches for analyzing high throughput genetic and genomic data. Multiple project directions are available in statistical genetics (such as genetic epidemiology study in diverse, multi-ancestry datasets using genome-wide sequencing data, gene-environment interaction, meta-analysis) and genomics (such as single-cell omics analysis, multi-omics data integration, network analysis).

The training activities of this position will include data management, analysis, development and/or implementation of novel analytical approaches and bioinformatics tools for data analysis, implementation of pipelines, interpretation and presentation of analysis results, and writing manuscripts.

866 days ago

Postdoctoral

Singapore Institute for Clinical Sciences -

Research Fellow – Bioinformatics / Molecular Epidemiology – Perinatal and Child Health and Development

A two-year position at the Singapore Institute for Clinical Sciences is available to a highly-motivated postdoctoral researcher in bioinformatics and/or molecular epidemiology in the area of reproductive, perinatal, and pediatric epidemiology, with particular training and expertise in transcriptomics and epigenomics. The candidate will develop a competitive research portfolio using class-leading multimodal data from up to three longitudinal birth cohort studies (GUSTO, N = ~1200 enrolled; S-PRESTO, N = ~1000 enrolled; and MAMS, N = ~2000 anticipated) in collaboration with local research hospitals, top research universities, government research entities, and a broad network of international collaborators.

The cohorts represent world-class efforts in deep pheno- and geno-typing, with available measures including: clinical characteristics; sociodemographics and spatiotemporal data; parenting and child behaviors; child neurodevelopmental assessment; state-of-the-art brain and body imaging; and numerous –omics (metabolome; (epi)genome; transcriptome; microbiome). A large biorepository (e.g. hair, saliva, urine, blood) has been formed. Details on available data and samples for GUSTO/S-PRESTO can be found at: gustodatavault.sg

Opportunities for further training, mentorship, and collaboration, including out-placement with a data science industry partner may be possible. Incumbent will have access to a highly interdisciplinary local research environment at SICS; A*STAR; Duke-NUS; NUS School of Public Health; NUS School of Medicine; NTU, etc. with the goal of supporting the incumbent’s long-term career goals. SICS is a dynamic working environment with dozens of postdoctoral peers working in such diverse domains as eating behaviors, neurodevelopment, allergy, growth and metabolism, parenting, -omics, brain and body imaging, and oral health.

883 days ago

Postdoctoral

Ontario Institute for Cancer Research -

Position: Postdoctoral Fellow
Site: MaRS Centre, Toronto
Department: Diagnostic Development
Reports To: Principal Research Scientist
Salary:  Commensurate with level of experience
Hours: 35 hours/week
Status: Full-time, Temporary (2 year contract)

The Ontario Institute for Cancer Research (OICR) is seeking a highly motivated and qualified postdoctoral fellow who possesses relevant training in proteomics or molecular biology and interested in cancer biology to join the Diagnostic Development program. This is a 2-year contract with the potential to extend.

The successful candidate will join a highly dynamic and translational research program in biomarker discovery in various cancer types. The program aims to develop personalized medicine approaches that maximize the chance of positive outcomes for those diagnosed with cancer. The project will use clinical cohorts to examine the predictive and translational value of the tumour and the immune microenvironment on treatment. The aim of the project is to develop and perform spatial transcriptomic and proteomic profiling to identify and characterise targets and associated biomarkers for cancer treatment.

The MaRS Centre has a mandatory COVID-19 vaccination policy in place that requires proof of full COVID-19 vaccination or proof of a medical exemption issued pursuant to the Government of Ontario guidelines.  Accordingly, as a condition of employment, new employees who are required to work on-site are required to be fully vaccinated for COVID-19 subject to the duty to accommodate on the basis of protected grounds pursuant to the Ontario Human Rights Code.

Fully vaccinated is defined as having received all of the required doses of a Health Canada approved vaccine and having received the final dose at least 14 days before your employment start date.

As described above, the requirement to be fully vaccinated is subject to the Ontario Human Rights Code. If the candidate is unable to receive the COVID-19 vaccine for a reason protected by the Code, requests for accommodation from the vaccine policy will be assessed on a case-by-case basis.

Learn more about working at OICR here

883 days ago

Postdoctoral

Ontario Institute for Cancer Research -

Position: Postdoctoral Fellow in Computational Genomics
Site: MaRS Centre, Toronto
Department: Computational Biology
Reports To: Shraddha Pai
Salary: Commensurate with level of experience
Hours: 35 hours/week
Status: Full-time, Temporary (1-year contract)

The Ontario Institute for Cancer Research (OICR) is seeking a dynamic, collaborative postdoctoral fellow to join a team developing computational algorithms for cancer drug target prioritization using genomics, biological networks, and systems medicine-based approaches.

The goal of the project is to create an algorithm to prioritize lead molecules for drug targeting by integrating prior ‘omic and non-‘omic knowledge to maximize functional relevance and minimize off-target effects. The algorithm will use network-based approaches, and will incorporate genomic prior knowledge such as tissue-specific transcriptomic and proteomic profiles, known oncogenic mutations, and target druggability, as well as non-‘omic sources such as reports of adverse drug reactions. The successful candidate will lead method development, benchmarking for method optimization, and manuscript writing of results. Prioritized molecules will be experimentally verified by members of the team from OICR’s Drug Discovery group.

The Pai Lab at the Ontario Institute for Cancer Research develops computational methods for precision medicine, with a focus on network and systems medicine. The project is a collaboration between the Ontario Institute for Cancer Research’s Adaptive Oncology and Drug Discovery teams, which includes the labs of Rima Al-Awar, Richard Marcellus, Lincoln Stein and Shraddha Pai. While this posting is for a one year initial contract, a contract extension for a second year is a strong possibility.

The successful candidate will gain the experience of working in an interdisciplinary team of computational biologists and pharmacologists, and be exposed to the process of drug discovery technology development.  The candidate will be part of the rich scientific environment of the OICR, with opportunities for development of technical, leadership, and entrepreneurial skills. The candidate will also have the opportunity to learn about the space for biomedical technology development for commercialization.

The MaRS Centre has a mandatory COVID-19 vaccination policy in place that requires proof of full COVID-19 vaccination or proof of a medical exemption issued pursuant to the Government of Ontario guidelines.  Accordingly, as a condition of employment, new employees who are required to work on-site are required to be fully vaccinated for COVID-19 subject to the duty to accommodate on the basis of protected grounds pursuant to the Ontario Human Rights Code.

Fully vaccinated is defined as having received all of the required doses of a Health Canada approved vaccine and having received the final dose at least 14 days before your employment start date.

As described above, the requirement to be fully vaccinated is subject to the Ontario Human Rights Code. If the candidate is unable to receive the COVID-19 vaccine for a reason protected by the Code, requests for accommodation from the vaccine policy will be assessed on a case-by-case basis.

To learn more about working at OICR, visit our career page.