Jobs
74 days ago
UQAM -
Microbial biomarkers to improve the efficacy of GDNF treatment for Hirschsprung disease
Context
Hirschsprung disease is a deadly congenital malformation where the enteric nervous system (ENS) is missing from the colon. Recently, we found that a GDNF-based treatment can induce the formation of a new ENS in the colon of mouse models of Hirschsprung disease, and significantly improve gastrointestinal functions and survival of these mice. However, we have observed variability in the response to GDNF treatment among individuals, with some mice failing to respond while others respond positively. In collaboration with our project partner Neurenati, we are carrying out studies to understand why, and thereby improve the efficacy of the treatment.
90 days ago
University of Guelph / Ontario Veterinary College -
Project Title: The H5Nx Genomic Landscape: Predictive Modelling of Host and Antigenic Transitions
A funded Postdoctoral Fellow opportunity is available in under the co-supervision of Dr. Zvonimir Poljak (University of Guelph) and Dr. Finlay Maguire (Dalhousie University).
This is a full-time one-year position, with the possibility of extension, at the University of Guelph. This position is supported by the Canadian Institute of Health Research/Public Health Agency of Canada’s Avian Influenza One Health Research Funding Opportunity with contributions from NSERC.
119 days ago
University of Alberta -
Date: September 23, 2024
Postdoc/PhD positions in saRNA for Vaccine Development
We are seeking applications for multiple Senior Researcher positions, available immediately for exceptionally motivated Postdoctoral Fellows or PhD students. These positions offer a unique opportunity to contribute to a pioneering project applying artificial intelligence and machine learning to the development of RNA vaccines against emerging viral threats such as Influenza, Lassa, and Orthopox viruses.
Project Overview: This ambitious project utilises self-amplifying RNA (saRNA) technology, which offers the potential for more potent immune responses at lower doses compared to traditional mRNA vaccines. Our approach focuses on the use of structural RNA bioinformatics to design vaccine candidates and predict the effects of viral mutations, enhancing our ability to respond rapidly to evolving pandemic threats.
135 days ago
University of British Columbia -
A post-doctoral fellowships (PDF) position in the field of machine learning/computational biology is available in the School of Biomedical Engineering and Department of Pathology and Laboratory Medicine at the University of British Columbia/Vancouver General Hospital. The incumbents will join an interdisciplinary team working to establish a program on machine learning applications in pathology and genomics. Candidates are expected to have extensive experience in one or more of the following areas: diverse areas of machine learning and statistics especially deep neural networks, statistics, and image processing.
The candidate will play an important role in the project team, including authoring grants, conducting large-scale international projects, managing collaborations, disseminating research findings, and assisting in managing junior lab members.
The successful candidate will report to the Principal Investigator (Director of AI Research at OVCARE, Dr. Ali Bashashati).
140 days ago
Broad Institute of MIT and Harvard, Imaging Platform -
There are two projects:
– Rapidly identifying disease phenotypes from rare disease variants, and drugs to reverse their impact (as part of the NIH IGVF Consortium https://www.youtube.com/watch?
– Using Cell Painting, transcriptomics, and proteomics data to predict the toxicity of drugs and agrochemicals (as part of the OASIS Consortium https://oasisconsortium.org)Both projects will have copious data produced by this time next year!
Learn more here and apply: https://docs.google.com/