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8 days ago

MSc PhD

Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval -

We are seeking a talented Master’s or PhD student in Computational Biology or Bioinformatics to join our Translational and Integrative Pathology Lab, investigating the molecular and spatial landscape of neuroendocrine lung neoplasms. The successful candidate will contribute to a cutting-edge project focused on Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)—a rare and understudied precursor lesion that can evolve into carcinoid tumors.

 

Leveraging spatial transcriptomics, deep genomic profiling, and tumor microenvironment (TME) analysis, this role will help uncover the clonal evolution and molecular mechanisms driving disease progression. The position offers a unique opportunity to work with high-resolution spatial omics data and contribute to impactful discoveries in lung cancer biology.

203 days ago

MSc

Institut Universitaire de Cardiologie et de Pneumologie de Québec - Université Laval -

The English version follows the French.

Laboratoire : Le laboratoire de recherche en oncologie pulmonaire intégrative et translationnelle à l’Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ) – Université Laval (Faculté de Médecine) comprend une équipe multidisciplinaire composée de pathologistes thoraciques et moléculaires, généticiens, biologistes computationnels, bioinformaticiens, professionnels de recherches et étudiants gradués. Il est situé dans un centre de recherche de renommée internationale au sein duquel travaillent en collaboration des chercheurs impliqués en recherche fondamentale, en oncologie, en chirurgie thoracique et en pneumologie. Les membres du laboratoire travaillent en étroite collaboration avec les équipes cliniques de l’IUCPQ, la biobanque institutionnelle et des équipes de l’industrie pharmaceutique et des biotechnologies pour répondre à de grands enjeux ciblés sur les besoins des patients. Les projets du laboratoire intègrent l’analyses de multiples jeux de données -omiques, comme la transcriptomique et la protéomique spatiale, afin de répondre à des questions cliniques centrées sur les besoins des patients.

Poste : Nous cherchons un étudiant(e) à la maîtrise pour intégrer notre équipe de recherche à l’automne 2025 ou l’hiver 2026. L’étudiant(e) sera encouragé(e) à faire un stage rémunéré de 3 mois débutant à l’été 2025 avant le début de sa maîtrise. L’étudiant(e) travaillera sous la supervision des Dr. Fabien Lamaze (biologiste computationnel, chercheur associé), Dr. Sébastien Renault (bioinformaticien) et Dre. Andréanne Gagné (pathologiste et chercheur).

Description du projet : L’étudiant(e) sera impliqué(e) dans un projet de recherche translationnel sur un sous-type de cancer du poumon très agressif pour lequel il y a peu d’options thérapeutiques, soit les carcinomes à petites cellules du poumon (SCLC). Récemment, des analyses transcriptomiques ont permis de classer les SCLC en quatre sous-groupes qui ont une valeur potentiellement pronostique et thérapeutique. L’objectif est de corréler ces sous-groupes avec le pronostic des patients et d’identifier leurs mécanismes de régulation. Ceci permettra de mieux comprendre la biologie de ces tumeurs afin de mieux prédire le comportement clinique des tumeurs, trouver des mécanismes potentiels à des thérapies existantes et/ou découvrir de nouvelles avenues thérapeutiques. Via la biobanque institutionnelle, l’équipe a accès à une large cohorte unique et bien caractérisée. Ceci permettra à l’étudiant(e) sélectionné(e) de travailler sur l’analyse des données en utilisant des outils de bioinformatique, d’apprentissage machine, de transcriptique, de transcriptomique spatiale et de pathomique.

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Lab: The Integrative and Translational Lung Oncology Research Laboratory at the Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ) – Université Laval (Faculty of Medicine) is a multidisciplinary team composed of thoracic and molecular pathologists, geneticists, computational biologists, bioinformaticians, research professionals, and graduate students. The lab is located within a world-renowned research center where researchers in basic science, oncology, thoracic surgery, and pulmonology collaborate closely. The lab works in tight collaboration with IUCPQ’s clinical teams, the institutional biobank, as well as pharmaceutical and biotechnology industry partners to address major challenges focused on patient needs. Projects integrate the analysis of multiple -omics datasets, such as transcriptomic and spatial proteomic mapping, to answer clinically driven, patient-centered questions.

Position: We are seeking a Master’s student to join our research team starting in Fall 2025 or Winter 2026. The student will be encouraged to complete a paid 3-month internship beginning in Summer 2025 prior to starting their Master’s. The student will work under the supervision of Dr. Fabien Lamaze (Computational Biologist, Associate Researcher), Dr. Sébastien Renault (Bioinformatician), and Dr. Andréanne Gagné (Pathologist and Researcher).

Project Description: The student will be involved in a translational research project focused on a highly aggressive subtype of lung cancer with limited therapeutic options: small cell lung carcinoma (SCLC). Recent transcriptomic analyses have classified SCLC into four molecular subtypes with potential prognostic and therapeutic relevance. The project’s objective is to correlate these subtypes with patient outcomes and identify their regulatory mechanisms. This work aims to improve our understanding of SCLC biology to better predict clinical behavior, uncover mechanisms exploitable by existing therapies, and potentially discover new therapeutic avenues.Through the institutional biobank, the team has access to a large, unique, and well-characterized cohort. The selected student will work on data analysis using bioinformatics, machine learning, transcriptomics, spatial transcriptomics, and pathomics tools.

870 days ago

MSc PhD

University of Ottawa -

The Mer lab ( https://merlab.github.io/ ) at the University of Ottawa, Canada has multiple fully funded graduate (MSc and Ph.D.) student positions available. We are looking for highly motivated and skilled individuals to work in the areas of bioinformatics, machine learning, genomic data analysis, and personalized medicine.
We are located at the Department of Biochemistry, Microbiology and Immunology  (www.uottawa.ca/faculty-medicine/biochemistry-microbiology-immunology ) and part of the Ottawa-Carleton Joint Bioinformatics Program (www.bioinformatics.uottawa.ca ). Students with degrees in computer science (or related fields) will also have the opportunity to enroll in the School of Electrical Engineering and Computer Science graduate program (www.uottawa.ca/faculty-engineering/school-electrical-engineering-computer-science ).

946 days ago

MSc

Ontario Institute for Cancer Research -

Position:                      Research Associate II – Outreach Coordinator
Location:                     MaRS Centre, Toronto
Department:                Computational Biology

Reports To:                 Project Manager, Reactome
Salary:                         Commensurate with level of experience
Hours:                          Flexible (Full-time or Part-time options up to 35 hours/week)
Job Type:                    Hybrid or Remote
Status:                         Full-time Permanent or Renewable Contract

The Ontario Institute for Cancer Research (OICR) is seeking an experienced and highly motivated individual to act as Outreach Coordinator for the Reactome project.

Reactome (reactome.org) is an open access and open-source curated database of human biomolecular pathways. Pathways are assembled from the published literature by Masters- and PhD-level scientists and integrated into powerful bioinformatics analysis tools on the Reactome website. Our interdisciplinary and international team comprises biologists, software engineers, and user interface designers. 

As Reactome Outreach Coordinator, you will lead our community outreach activities, strengthening existing collaborations and developing initiatives to foster new ones. Working with the software and curatorial teams, you will coordinate Reactome communications, including conference presentations, workshops, scientific and lay papers, and social media. You will develop education and training materials for in person and online learning and will contribute to the documentation on the Reactome web site.

 

948 days ago

MSc PhD

The University of Western Ontario -

We have several graduate positions (PhD or MSc) available for individuals interested in single-cell molecular technologies, bioinformatics and data science. Possible research topics include:

– Identifying signatures to predict treatment response in breast cancer

– Single-cell genomics of immune responses to cancer

– Microbial single-cell transcriptomics

New students can join the lab via the Anatomy and Cell Biology or Biochemistry graduate programs and will have the opportunity to join Western’s Collaborative Specialization in Machine Learning in Health and Biomedical Sciences.