Jobs
822 days ago
Dalhousie University -
Funded PhD developing tools to automatically identify new and emerging antimicrobial resistance
The main aim of the PhD will be the development and evaluation of methods for automatically identifying novel and evolving antimicrobial resistance (AMR) genes. AMR is a growing global health crisis that threatens the function of modern medicine. Genomically informed diagnostics and surveillance have been identified as key activities to try and ameliorate this crisis. Currently, AMR gene prediction results (such those generated by CARD’s RGI) require a lot of expertise and manual analyses in order to identify potentially important or worrying emergent genes. This project seeks to use existing data from efforts to characterise AMR in large genome databases along with associated phylogenetic, spatiotemporal, and phenotypic data to develop means of automating these analyses.
The PhD will take place within the Maguire Lab in the Faculty Computer Science & Faculty of Medicine (Department of Community Health & Epidemiology) at Dalhousie University. The specific PhD program (CS, Epidemiology, Interdisciplinary or potentially Microbiology/Biochemistry) will depend on the specific candidate background. Through this research the candidate will gain skills in the analysis of large complex datasets, the development of bioinformatic tools and web resources, and translating genomic data into clinical and public health insights.
This project will also involve existing collaborations with clinicians (Toronto’s Shared Hospital Laboratory and Sunnybrook Research Institute), public health agencies (PHAC/NML & CFIA/NCFAD), and infectious disease researchers including local experts in evolutionary microbiology and Dr. Andrew McArthur’s Comprehensive Antibiotic Resistance Database (card.mcmaster.ca) group at McMaster University.
838 days ago
Health Sciences North Research Institute -
The Verschoor laboratory is looking for a prospective PhD student to investigate the utility of epigenome-wide DNA methylation patterns as a tool to understand and define the risk of acute and long-term health outcomes. Current areas of interest include: 1) the epigenomic basis of chronic inflammation and its relation to health trajectories in older adults, and 2) the oral methylome as an indicator of treatment-related complications and survivorship in head and neck cancer patients. Our laboratory in situated at the Health Sciences North Research Institute in Sudbury, Ontario (hsnri.ca) and is affiliated with the Northern Ontario School of Medicine University (nosm.ca) and the School of Natural Sciences at Laurentian University (laurentian.ca/school/natural-sciences).
977 days ago
McMaster University -
The Wilson Pregnancy Lab is located at McMaster University, in the Department of Obstetrics and Gynaecology, in Hamilton, Ontario, Canada The Wilson Pregnancy Lab, under the direction of Dr. Samantha Wilson, is an ‘omics research group with an emphasis on genomics, epigenomics, and transcriptomics. Our goal is to develop non-invasive methods to predict pregnancy complications before they occur, and to understand the cause of placental dysfunction. We work in the fields of genomics, computational biology, and reproduction.
We are seeking 1-2 talented graduate students for May or September entry 2023. We have several projects available related to genomic and epigenomic signatures of cell-free placental DNA and placental dysfunction. These projects use a variety of multi-omic data, mostly sequencing based, with some microarray data.
We are looking for prospective students with a strong background in genetics, with at least basic experience in computational biology. Experience in a unix environment, high performance computing, and scripting in R, Python and/or bash are assets.
To apply to a graduate student position within the Wilson Pregnancy Lab, please email a copy of your CV (PDF format), a cover letter explaining your research interests, contact information for 3 references, and transcripts to wilsos66[at]mcmaster.ca with the subject line “[MSc or PhD] Application: [Your Name]”.
Potential candidates will also need to meet the entrance requirements for either the Biochemistry graduate program or the Medical Science Graduate program.
For more information, visit the Wilson lab website at wilsonpregnancylab.com
1138 days ago
Canada's Michael Smith Genome Sciences Centre (GSC) -
Dr. Aly Karsan and the Karsan Lab team are seeking a Research Programmer to join a Marathon of Hope Cancer Centre research project.
The successful applicant will be working with other research programmers in the Karsan lab to develop data analysis pipelines for various next-generation sequencing (NGS) data such as—but not limited to—scRNA-Seq, targeted sequencing, ATAC-Seq, and BS-Seq. We seek candidates with strong analytical and programming skills to research, develop, and improve our research pipelines for studying cancer evolution. The role is ideally suited to detail-oriented individuals with a strong interest in data analysis, research, and scientific programming within a high throughput academic setting.
By working within the Karasn Lab at the GSC, you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada. The Karsan lab has a history of strong publications and a diverse computational biology core for knowledge sharing, collaboration, and support.
This is a non-union position funded by a BC Cancer Foundation Grant. We offer a competitive salary, excellent benefits and significant career development opportunities. Remote applicants are encouraged to apply.
1151 days ago
Western University -
Dr. Pingzhao Hu at The Department of Biochemistry at Western University has funded graduate student (MSc or Ph.D.) positions in Bioinformatics/Statistical Genetics. More information can be found at http://www.hu-bioinformaticslab.org/positions.html. Please be noted that my lab will be moving to Western University on September 1, 2022.