I am a computational biologist with a primary focus on the analysis of genomics data related to transcription and gene regulation. My background includes undergraduate studies in mathematics and cell biology, graduate studies in cellular biology and cancer prevention and post-doctoral training in bioinformatics. My lab created the JASPAR database of transcription factor binding profiles and methods for the identification of cis-regulatory regions in the human genome. Being based at BC Children’s Hospital and the Centre for Molecular Medicine and Therapeutics, a second research focus has emerged at the interface between researchers, clinicians and patients arising from the use of whole genome sequencing for the diagnosis of genetic disorders. Our ongoing work focuses on the pursuit of equity for Indigenous peoples through the Silent Genomes Project. Working with clinical partners, my lab maintains IEMbase, an international knowledgebase related to inborn errors in metabolism.
Website: https://cisreg.ca/