David S. Guttman is a Professor in the University of Toronto Department of Cell & Systems Biology and Director of the Centre for the Analysis of Genome Evolution & Function. His research focuses on deciphering how bacteria adapt to and manipulate their hosts, emphasizing the evolution of bacterial host specificity and virulence and the dual role of secreted pathogen effectors as both virulence factors and immune elicitors. His group is particularly fascinated by the scope and impact of natural genetic diversity on these host-microbe interactions. The Guttman lab uses a multidisciplinary approach that harnesses comparative and evolutionary genomics, genetics, molecular biology, microbiology, plant biology, pathology, bioinformatics, and statistical genetics to gain insight into how pathogen evolution influences the outcome of host-pathogen interactions.
Website: https://guttman.csb.utoronto.ca/