Our group focuses on understanding the molecular events underlying the progression of early breast lesions. We often use different types of high-throughput profiling methods to provide comprehensive molecular overviews of the lesion, its microenvironment and the patient systemic response. We also develop new methods to subject cells and tissues to multiple genetic interventions simultaneously. The profiling information is used to build computational tools to understand higher-order interactions in complex biological systems and pathways. Our goal is to develop tools for end-points with clinical relevance and to use these tools to characterize events in tumoral progression.
Website: https://www.mikehallett.science/
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