Job Listings

The Morrissy Lab is seeking a highly motivated scientist with expertise in bioinformatics and data science to join our team as a Postdoctoral Associate focused on understanding immunotherapy responses in solid tumors. The candidate will use state-of-the-art analytic approaches to investigate multi-omics data and derive an in-depth understanding of tumor ecosystem dynamics in clinical samples from immunotherapy trials – including phenotypic and functional cell heterogeneity, tumor and microenvironment cell niches, and cellular crosstalk. This research is primarily focused on cohorts of single-patient and phase I clinical trial participants treated with CAR T-cells (see Zemp el, 2024, in revision at Nature; preprint on medRxiv), and identifying mechanisms of immunotherapy response and resistance from longitudinally-collected blood and tumor tissue samples. The candidate will employ innovative bioinformatics and machine learning approaches to integrate single cell and spatial datasets from clinical samples with data from ongoing preclinical studies, further incorporating genomics and proteomics profiles from in-house or public repositories.

Company Description: Roche Diagnostics is a global leader in healthcare diagnostics, committed to improving patient outcomes through innovative diagnostic solutions. With a focus on precision medicine and personalized healthcare, Roche Diagnostics develops and commercializes advanced diagnostic tests and technologies across various disease areas, including oncology, infectious diseases, and autoimmune disorders. Our mission is to empower healthcare professionals with accurate, timely, and actionable diagnostic insights to support informed clinical decision-making and improve patient care.   Job Description: We are seeking a talented and experienced AI expert in the field of bioinformatics and computational biology to join our dynamic team. In this role, the successful candidate will play a key role in the development and implementation of AI-driven approaches for the analysis, interpretation, and utilization of molecular data in diagnostic assays and platforms. Working closely with interdisciplinary teams of biologists, computer scientists, and domain experts, the AI expert will contribute to the advancement of Roche’s molecular diagnostic portfolio and drive innovation in precision diagnostics leveraging state-of-the-art methodologies and tools. A strong background in software development and data engineering will be a big advantage for this role. This could be a hydrid or remote position based on the location in Canada.