Bioinformatician

This is a full time position within the Arnie Charbonneau Cancer Institute reporting to Dr. Sorana Morrissy and Dr Augusto Faria Andrade, at the Cumming School of Medicine. The position is available beginning immediately for an appointment period of 12 months, with the option to extend for multiple years.

The University of Calgary’s Charbonneau Cancer Institute has a thriving immunotherapy research program focused on developing next-generation immunotherapies and delivering them to cancer patients in Alberta and beyond. In bringing together basic, translational and clinical scientists and supporting them to achieve a shared mission, this unique ecosystem for translational research produces knowledge, inventions, collaborations, and commercial opportunities. The bioinformatician role will be positioned within the Discovery and Innovation node of this program to (1) to identify and study novel therapeutic targets for immune therapy in solid tumors, including pediatric brain cancers, and (2) support collaborative research projects. The successful candidate will have responsibility at technical and intellectual levels.

The Bioinformatician will design and implement workflows for multi-omic datasets generated in-house and acquired from public data repositories. They will work closely and collaboratively with staff and trainees within and outside of the immunotherapy program to facilitate informatics needs towards translational medicine goals. Their work will focus on the genomics, machine learning, and translational medicine space. They will analyze data, prepare and deliver reports and presentations, attend and present their findings at local, national and international meetings, and contribute to manuscript and grant preparation. The Bioinformatician will play an integral role throughout the program and will benefit from opportunities for training and growth towards more senior roles. Ultimately, they will contribute to a scientific ecosystem that supports an integrated array of translational research within the Charbonneau Cancer Institute at the Cumming School of Medicine.

Research Design and Implementation

• Design and implement pipelines for analysis of sequencing datasets, including genomes, transcriptomes, proteomes, and spatial or single cell sequencing datasets from both pre-clinical and clinical samples
• Analyze experimental data, summarize and report findings
• Develop bespoke computational workflows and protocols
• Contribute to data assembly and writing of scientific manuscripts and grants
• Presenting research at local, national and international meetings is highly encouraged

Supervision and Collaboration

• Work collaboratively with other staff and trainees within the immunotherapy program to achieve shared goals
• Work collaboratively with multiple PIs and their teams on diverse projects related to their informatics analysis needs towards translational medicine
• Other tasks and responsibilities as they arise

• PhD degree Bioinformatics, Computer Science, Molecular Biology, or related field required.
• Minimum 2-3 years of relevant research experience, including experience in data science, genomics, bioinformatics, or machine learning
• Proficiency in at least one programming language (such as Python or R)
• Experience with Linux / Unix working environments, and high-performance computing clusters
• Expertise with analysis and algorithm development on complex NGS datasets
• Must be able to work both independently and in a team environment
• Detail oriented, organized, and strong written communication skills as evidenced by a record of publication and scholarship
• Track record of presenting research at local and national meetings
• Demonstrated communication, organization, problem solving, and interpersonal skills