Trevor Pugh, PhD
Scientist, Princess Margaret Cancer Centre, University Health Network
Assistant Professor, Department of Medical Biophysics, University of Toronto
I am focused on the application of genome sequence analysis as a routine clinical test, particularly as modern cancer treatments are predicated on genetic information. I am particularly interested in genome analysis of serial biopsies and circulating tumour DNA collected during clinical trials (particularly immunotherapies), genetic relationships amongst metastatic sites suggestive of effective combination therapies, and oncogenic mechanisms underlying rare tumours of unknown etiology including pediatric, breast, neuroendocrine, and gynecologic cancers. I also spend part of my time supporting diagnostic testing as a clinical molecular geneticist in the University Health Network Laboratory Medicine Program.
Research Interests: cancer genomics, clinical molecular genetics, data sharing