Research Technician, Bioinformatics & Cancer Research

Institution/Company:
OICR
Location:
Toronto, ON, Canada
Job Type:
  • Staff
Degree Level Required:
Bachelor's
Apply Now

Research Technician, Bioinformatics & Cancer Research

As a successful candidate, you will have extensive interest in large-data problems, excellent quantitative analysis skills and in-depth knowledge of cancer genomics. You will analyse diverse -omics datasets to explore the basic biology of cancer and to drive discovery of molecular biomarkers and personalised therapies. You will work closely with the team and the Principal Investigator on cancer genomics projects in collaborations with basic, translational, and clinical researchers at the OICR, in the excellent research community of Toronto and internationally. Your tasks will include:

Integrative analysis of multi-dimensional cancer genomics datasets using statistical and machine learning approaches; Pre-processing, normalization, and quality control of next-generation sequencing (WGS) and other –omics data;

Development of innovative computational methods and open-source bioinformatics software; Visualization and interpretation of –omics data with pathway and network information.

Responsibilities:

As a successful candidate, you will have extensive interest in large-data problems, excellent quantitative analysis skills and in-depth knowledge of cancer genomics. You will analyse diverse -omics datasets to explore the basic biology of cancer and to drive discovery of molecular biomarkers and personalised therapies. You will work closely with the team and the Principal Investigator on cancer genomics projects in collaborations with basic, translational, and clinical researchers at the OICR, in the excellent research community of Toronto and internationally. Your tasks will include:
Integrative analysis of multi-dimensional cancer genomics datasets using statistical and machine learning approaches;
Pre-processing, normalization, and quality control of next-generation sequencing (WGS) and other –omics data;
Development of innovative computational methods and open-source bioinformatics software;
Visualization and interpretation of –omics data with pathway and network information.

Qualifications:

Qualifications:

Undergraduate degree in bioinformatics, computational biology, genomics, or computer sciences required
Minimum 2 year of academic or professional experience in bioinformatics;
Strong scientific publication record in peer-reviewed journals on bioinformatics and/or cancer research;
Strong understanding and interest in molecular biology, genomics, and cancer;
Strong knowledge of basic statistics; machine learning skills are a definite plus;
Familiarity with the Linux or MacOSX environment, shell scripting and system tools; experience with high performance computing is an asset;
Minimum 2 years of experience with programming and data analysis in R, Python, Perl, Matlab or similar;
Minimum 2 years of experience with bioinformatics resources, databases, tools and common standard formats;
Minimum 2 years of experience in analysing next-generation sequencing and/or microarray data;
Ability to work independently as well as part of a fast-paced and collaborative team;
Excellent verbal and written communication skills in English.

Additional Information

OICR is an innovative cancer research institute located in the MaRS Centre in the Discovery District in downtown Toronto. OICR is addressing significant challenges in cancer research with multi-disciplinary, multi-institutional teams. New discoveries to prevent, detect and treat cancer will be moved from the bench to practical applications in patients. The OICR team is growing quickly. We are innovative, dedicated professionals who bring expertise to each of our roles. We are looking for individuals interested in being part of a culture of excellence that will result in Ontario being recognized internationally as a leading jurisdiction for cancer research.