Bioinformatician

Institution/Company:
Univerisity of British Columbia
Location:
Vancouver, BC, Canada
Job Type:
  • Staff (Full time)
Degree Level Required:
Bachelor's
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Bioinformatician

The Kobor Lab is seeking a highly motivated and ambitious individual to work as a bioinformatician/data analyst on various projects related to understanding the causes and consequences of variation in epigenetic marks across human populations. The successful applicant will be responsible for leading and contributing to a number of existing funded projects. These include population cohort studies that focus on the genomic embedding of early-life experiences in relationship to development and health across the lifespan. This work involves the acquisition of high-dimension datasets for genotyping, DNA methylation and mRNA expression and their integrative analysis with phenotype and environmental exposures.

The ideal applicant will possess a curiosity and passion for science, a talent for independent research, extensive knowledge of statistical genomics and/or epigenetics / gene regulation, and experience with bioinformatics.

Responsibilities:

• Performs statistical and bioinformatics analyses of high-throughput epigenomics and genotyping data to facilitate the interpretation of associations between molecular data with environment, stress and disease • Collaborates actively with others across the CMMT, UBC, and BCCRHI to problem solve and provide clarity on the application of bioinformatics approaches to understanding epigenetics, from molecular analysis in model organisms to population-scale studies of human epigenetic variation • Ensures the integrity of data in bioinformatics databases by performing quality control and working closely with other research personnel and collaborators on such issues • Evaluates the methods for the capture and transmission of epigenetic data and makes recommendations for the bioinformatics integration with related large datasets to derive higher order principles • Participates in meetings and phone/video conferences as project lead for multiple collaborations with local, national, and international groups on diverse projects related to children’s mental and physical health, and works with academics, clinical and community practitioners, and other professionals from multiple fields • Presents results to collaborators and the broader scientific community • Contributes to ongoing strategic planning for the ongoing bioinformatics analysis needs of the lab and assists with crafting of relevant sections in applications for potential funding sources • Contributes to writing scientific manuscripts • Updates Dr. Kobor and the group on the status of projects during lab meetings, in email correspondence and phone/video conferences • Maintains and develops up-to-date knowledge of current information technology techniques and tools, especially as they apply to bioinformatics analysis

Qualifications:

• A minimum of an undergraduate degree in a relevant discipline (genetics, computational biology, bioinformatics, bio-statistics), and a minimum of two years of experience in laboratory research involving genome technologies infrastructure, with knowledge of molecular biology, biochemistry, genetics, and epigenetics. • Proficiency in at least one programming language (R preferred). • Experience in writing executable R scripts, and debugging code. • Experience working with DNA methylation, genotyping, expression, and/or multi-dimensional genomics or population data. Knowledge with the development of novel packages/analysis pipelines. • Intermediate to high level understanding of statistical modeling and tests. • Experience with cluster computing and working in a Unix environment would be an asset. Proficiency with MS Word, Excel and databases. • Ability to communicate effectively verbally and in writing. • Ability to develop and maintain cooperative and productive working relationships. Ability to deal with a diversity of people in a calm, courteous, and effective manner. • Ability to adapt to changing priorities and work effectively under pressure to meet deadlines. • Ability to work effectively independently and in a team environment. • Ability to keep abreast of current developments and trends in the field of information technology. • Must conduct all activities in an ethical manner and treat funding information and research data confidentially.

  • How to Apply

    Please send CV and Cover Letter to Tanya Erb and Chaini Konwar. Applicants can apply through the UBC Careers Website until July 1, 2020 at: www.staffcareers.ubc.ca/37698