Hospital for Sick Children
Toronto, ON, Canada
Job Type:
  • Staff
Degree Level Required:
PhD, Masters
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We are looking for a highly motivated bioinformatician with practical experience in the processing and analysis of large genomic datasets including next-generation sequencing datasets to join a dynamic laboratory at the Hospital for Sick Children. Our group focuses on the biology of brain tumours of children and adults, with a primary aim to understand how the molecular programs in normal neural stem cells cause and sustain the growth of these hard-to-treat cancers. In addition, we are interested in brain tumour heterogeneity and how the diverse cell types that comprise these tumours contribute to tumour maintenance and therapeutic resistance.


Here’s What You’ll Get To Do: • You will be expected to process and analyze large genomic datasets including next-generation sequencing datasets, including the integration of genomic (WGS,WES), transcriptomic (RNA-seq) and epigenomic (DNAm, ATAC) datasets and single cell data analysis and integration • You will work closely with both wet and dry-lab scientists to collaboratively solve complex biological problems • You will work on several large collaborative concurrent projects/priorities • You will manage the dissemination of research findings for publication in peer-review journals and conferences.


Here’s What You’ll Need: • A PhD in bioinformatics, computational biology or similar, with a good publication record. Candidates with an MSc with several years of relevant work experience will also be considered. •Experience with HPC environments •Experience with bash scripting in a Linux environment and statistical analysis in R or Python. •Familiarity with public biomedical information resources such as genome browsers, data repositories and annotation databases  •Strong communication, data presentation and visualization skills •Preference for candidates with additional experience in the integration of genomic (WGS, WES), transcriptomic (RNA-seq) and epigenomic (DNAm, ATAC) datasets and single cell data analysis and integration •Preference for candidates with an understanding of the relevant concepts in cancer biology, as well as enthusiasm for further learning

  • How to Apply

    Please provide a cover letter and a current CV as a single PDF including a publication list and names of two references. Please note that only candidates eligible to work in Canada can be considered for this position. We thank all applicants for applying, however, only those selected for an interview will be contacted.