Bioinformatics Links Directory New Links http://bioinformatics.ca/links_directory en Recently added links to the directory. LOVD http://www.lovd.nl/2.0/ The Leiden Open (source) Variation Database (LOVD) To provides a flexible, freely available tool for the gene-centered collection and display of DNA variations. Mutalyzer http://www.lovd.nl/mutalyzer/1.0.1/ Mutalyzer aims to support checks of sequence variant nomenclature according to the guidelines of the Human Genome Variation Society. Human Genome Variation Nomenclature http://www.hgvs.org/rec.html The Human Genome Society has established a committee to suggest standards for the description of sequence variants in DNA, RNA, and protein sequences. The standards are linked here. InteroPORC http://biodev.extra.cea.fr/interoporc/ InteroPorc is an automatic prediction tool to infer protein-protein interaction networks. It is applicable for any species present in the Integr8 database (more than 1500 organisms). The method combines known interactions and clusters of orthologous proteins. The tool can be downloaded or used through the web application. INTEGRALL http://integrall.bio.ua.pt/ INTEGRALL is a freely available, text-based search system developed to collect and organize information on integrons. There are more than 4800 integron sequences in the database.